Klostilbegit (clomiphene) – organic compound, hormonal preparation from the group of selective estrogen receptor modulators (SERMs). The drug is blocking the action of female sex hormones – estrogen. It is used in the treatment of infertility due to ovulation disorders . It is also used by people who are taking a drug, klostilbegit facilitates its side effects. acquire Klostilbegit you can online pharmacy EvroMedics, cost of 1 pills 39 hryvnia. call (073) 544-744-6.
On the preparation
Clomid acts on tissue containing estrogen receptors – ovary, endometrium, Cervix, vagina. It inhibits the action of estrogen on gonadotropin secretion, which leads to an increase in their blood levels. Gonadotropins stimulate the production of hormones in the ovaries (increase estrogen levels in the blood) and promote the growth and development of ovarian follicles , which ruptures and releases the egg. Thus drug recommend to use women with infertility, with ovulation disorders, including patients with PCOS (Polycystic ovary syndrome).
note! Sometimes two or more oocytes are extracted from the influence of clomiphene, why women, taking Clomid, there is a risk of multiple pregnancy.
The drug does not exhibit progestin, androgenic or anti-androgenic effect and does not affect the regulation of pituitary hormones of the adrenal or thyroid .
Clomiphene is also used in the pharmacological doping as a medicament, which reduces the side effects of steroids. Since this drug blocks estrogen receptors, it reduces the effects of estrogen action of steroid hormones, such as gynecomastia. The drug is banned for athletes World Anti-Doping Agency.
note! Clomiphene should not be used during pregnancy because of the risk of violations in the process of development of the fetus.
Side effects
- over-stimulation of the ovaries,
- tides,
- abdominal discomfort,
- nausea,
- vomiting,
- depression,
- insomnia,
- headache,
- hypersensitivity chest.
If detected ovarian hyperstimulation treatment should be discontinued.
analyzes 2018 year indicate, that long-term use of clomiphene may lead to increased risk of cancer, therefore it is advisable to limit the time of its adoption 6 ovulatory cycles. These findings need to be confirmed in animal and clinical trials research.
dosage
The drug should be used in accordance with the doctor's instructions, because the dosage must be selected individually for each patient. Usually 50 mg for 5 days, starting with the first five days of the menstrual cycle (preferably from the second day).
note! Long-term use is not recommended (more 6 months) due to an increased risk of ovarian cancer.
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